Since launching our new Trilostane monitoring profile it has proved to be a very effective and useful screening profile to detect other underlying problems in dogs. These may be missed, and inappropriately ascribed to the hyperadrenocorticism, when simply performing the regular ACTH stimulation test to assess the effectiveness of the current Trilostane dose. Any additional problems revealed with this broader screening can be further investigated and hopefully dealt with before they have progressed too far.
When using Trilostane in dogs it is recommended to monitor biochemistry parameters at regular intervals particularly checking for primary hepatic and renal disease, and diabetes mellitus.
Any overdosage may affect sodium and potassium levels as well as decreasing cortisol levels.
We have therefore developed a Trilostane monitoring profile which includes:
ACTH stim test, Total protein, Albumin, Globulin, A/G ratio, Urea, Creatine, Glucose, ALT, ALP, Na, K and Na:K ratio
Sampling requirement: 2 serum samples.